Twice-a-year injection could replace daily tablets to treat high blood pressure

High blood pressure could be treated with an injection every six months instead of a daily tablet as part of a new trial of the condition.

Scientists are testing the approach in what they said is a world first in how hypertension, or high blood pressure, could be treated.

Around a third of adults in the UK have high blood pressure, but many may not be aware of it, says the National Health Service.

Although it often has no noticeable symptoms, if hypertension is not treated, it can increase the risk of heart attacks and strokes.

Around 100 patients across the UK will be part of the 630 patients around the world involved in the new research from Queen Mary University of London and Barts Health NHS Trust.

People diagnosed with high blood pressure typically take tablets once a day to control the condition, the researchers said.

The British Heart Foundation said that while there wasn’t always an explanation for the cause of high blood pressure, most people developed it because of their diet, lifestyle or a medical condition.

This study, funded by Alnylam Pharmaceuticals and supported by the National Institute for Health and Care Research, runs for three years.

“We are excited to test this first-of-its-kind approach to investigate whether it is safe and effective for the treatment of high blood pressure,” said Dr. Manish Saxena, study leader and deputy clinical director at Queen Mary University.

“It’s early days, but our last hope is that the treatment proves to be a practical, safe and more manageable solution to combat high blood pressure.

“Twice-yearly treatment with injections under the skin would provide a better alternative to taking daily medications, which we believe would be good news for patients and make hypertension treatment more convenient.”

Updated: April 27, 2022, 4:32 am

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